Product Name :
NF-L Rabbit Polyclonal Antibody
Predicted band size :
62 kDa
Observed band size :
68 kDa
Synonyms:
68 kDa neurofilament protein antibody 68kDa Neurofilament antibody 68kDa neurofilament protein antibody CMT1F antibody CMT2E antibody FLJ53642 antibody Light molecular weight neurofilament protein antibody NEFL antibody Neurofilament light antibody Neurofilament light polypeptide 68kDa antibody 展开
Function :
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Recombinant protein within human NF-L aa 1-543 / 543.1231892-74-2 Chemscene
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IHC-P, FC
Coupling :
unconjugated
Clone number:
RRID:
AB_3096652
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.1250997-56-8 web Aliquot store at -20℃.PMID:33715971 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 62 kDa
Positive control :
Rat brain tissue lysate, mouse hippocampus tissue lysate, rat hippocampus tissue lysate, human brain tissue lysate, SH-SY5Y, human cerebellum tissue, mouse cerebellum tissue, rat cerebellum tissue.